The analysis of DNA methylation has technical features that make it a robust, routinely applicable technology:
For regenerative medicine purposes those characteristics are most relevant, since implants need to be helpful and harmless in the long run. Epiontis uses a proprietary "question-based" targeted approach to detect cell-type-specific biomarkers. Applying a chemical procedure, which specifically converts DNA at the cytosine position, Epiontis analyzes the methylation status of sample material. The analysis of thousands of cytosine positions in various genes allows the rapid identification of differences in their methylation statuses. Our studies have shown that DNA-methylation patterns are cell-type specific and results indicate that characteristic profiles are exhibited in many, if not all, tissues. These characteristic profiles can be used to determine the quality of cellular products.
